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Use of a bilayer biodegradable synthetic dermal matrix for the management of defects arising from necrotising fasciitis

Care can be divided into two overlapping phases. The first aim is the expedient surgical control of infection to achieve wound control and medical management of the effects of sepsis (e.g.,...

The influence of adequate debridement and placental-derived allografts on diabetic foot ulcers

Prospectively collected data from patients enrolled in two Institutional Review Board-approved RCTs (EFDFU003 and ECDFU001),14,22 and Medicare claims from 2015–2019 were retrospectively evaluated..

The characteristics and impact of hard-to-heal wounds: results of a standardised survey

The data reported in this study were collected via wound care surveys across 10 community wound care providers in the UK, Ireland, Finland, Norway and Denmark between February and August of 2017...

Treating hard-to-heal ulcers: biocellulose with nanosilver compared with silver sulfadiazine

To evaluate the efficacy of biocellulose with blue nanosilver, compared with silver sulfadiazine cream in the treatment of hard-to-heal diabetic ulcers..

Cost-utility of a biofilm-disrupting gel versus standard of care in chronic wounds: a Markov microsimulation model based on a randomised controlled trial

Although there were a few VLUs in groups 1 and 2 and one PU in group 1, the differences in utility between unhealed and healed states are similar for these wounds compared to DFUs.17 (The difference...

Topical oxygen treatment relieves pain from hard-to-heal leg ulcers and improves healing: a case report

A 74-year-old male patient with insulin-treated type 1 diabetes for more than 50 years, and with a previous history of foot ulceration, was referred to the Karolinska University Hospital dermatology...

Concurrent validity of biofilm detection by wound blotting on hard-to-heal wounds

This study showed concurrent validity with reference to native PAGE analysis for identifying and quantifying biofilm components through in vitro, in vivo and clinical investigations, as well as...

Efficacy of MMP-inhibiting wound dressings in the treatment of hard-to-heal wounds: a systematic review

Research, on the course of physiological wound healing and those wounds developing chronicity, uncovered key roles for matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases...

Does social support impact on venous ulcer healing or recurrence?

A search was conducted to retrieve any literature which specifically focused on the role of social support in patients with chronic wounds and/or venous leg ulceration. Electronic databases MEDLINE...

Theories of stress and coping and how they relate to individuals with venous leg ulceration

Mr B is a 63-year-old male. He is married, has a busy social life, and works full-time in a professional occupation. He has had recurrent venous leg ulcers for the last 10 years. This wound is in a...

Spirituality and subjective wellbeing in patients with lower-limb ulceration

This was a prospective, descriptive, analytical, clinical study conducted from December 2011 to October 2012. The study was approved by the research ethics committee of the Sapucaí Valley University...

Healing outcomes and predictors among patients with venous leg ulcers treated with compression therapy

A search was conducted on the PubMed and CINAHL databases from 2009–2019, using MeSH key terms of ‘venous leg ulcers’, ‘compression therapy’, ‘delayed healing’, ‘non-healing’ and ‘wound healing’. The...

Chronic venous insufficiency: a comprehensive review of management

A comprehensive literature review of medical textbooks and journals was undertaken. Chapters and articles discussing the pathophysiology of CVI and its sequelae were included. A PubMed search of...

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