A comparative analysis of skin substitutes used in the management of diabetic foot ulcers

DFUs that do not heal with standard care alone can be successfully treated with skin substitutes. However, these skin substitutes can be expensive, and once their use is initiated, treatment may still...

Management of diabetic foot ulcers: evaluation of case studies

Patients with slow-healing, static, or deteriorating DFUs were selected by clinicians to take part in an evaluation of AQAg+. The clinicians were experienced in podiatry, and had previous experience...

A review of the evidence for adjustable compression wrap devices

These adjustable devices consist of low-elastic material sections that wrap across the limb and are secured with hook and loop fasteners. They are designed for self-application over the short or long...

Platelet-rich plasma, bilayered acellular matrix grafting and negative pressure wound therapy in diabetic foot infection

A 35-year-old male who was diagnosed with type 2 diabetes 5 years ago presented at the Southern Arizona Limb Salvage Alliance (SALSA), following an accident where a nail pierced his left foot. The...

Lower extremity wound characteristics

Lower extremity wound characteristics.

Focus: lower extremity wounds

The static stiffness index: an important parameter to characterise compression therapy in vivo

Stiffness is the rigidity of an object, i.e. the extent to which it resists deformation in response to an applied force. The term was introduced into the CEN document of the European Committee of...

Healing of chronic sickle cell disease-associated foot and ankle wounds using transdermal continuous oxygen therapy

We performed our pilot study of the portable device EPIFLO (Ogenix), which delivers oxygen transdermally to the wound site. The device we used measures only 5 × 6.3 × 2.5 cm, weighs 100 g, is silent,...

The role of dressings in the prevention of pressure ulcers

‘Localized injury to the skin and/or underlying tissue usually over a bony prominence, as a result of pressure, or pressure in combination with shear’5 .

Patients' experiences of negative pressure wound therapy for the treatment of wounds: a review

There is evidence to show that significant pain is often experienced by patients during wound care, specifically in relation to dressing changes.10 Therefore, pain may impact on patients' concordance...

The aetiology of deep tissue injury: a literature review

Husain18 investigated the effects of different levels of pressure on skin and muscle tissue by applying a pressure cuff to the legs of rats and guinea pigs. Pressures of 50–800 mmHg were applied for...