This website is intended for healthcare professionals
This website is intended for healthcare professionals
Existing technologies directed to the treatment of biofilms are intended to either penetrate the EPS that encapsulates the bacteria in a biofilm, or use dispersing agents, which typically target a...
Wound infection is defined as the presence of microbes in the wound, which multiply and cause a host reaction either locally, in surrounding tissues, or systemically.6 This host reaction is manifested...
‘and if thy right eye offend thee, pluck it out, and cast it from thee: for it is profitable for thee that one of thy members should perish and, not that thy whole body should be cast into hell.’ .
Damage or stress causes cell necrosis. A necrotic cell loses membrane integrity and releases its intracellular contents including damage associated molecular patterns (DAMPs). These mediators may...
A microbial biofilm is an organised community of bacteria, enveloped within a self-produced matrix, that can attach, for example, to a wound surface (Fig 1).19 The formation of a differentiated,...
Biofilms are now a major area of research for both clinicians and scientists. This research has increased significantly in the past decade due to advancements in emerging technologies and techniques...
‘Today, debridement refers to deeply removing adherent, dead or contaminated tissue from a wound and must be clearly separated from the act of cleansing, defined as the removal of dirt (loose...
The databases searched were PubMed, Cochrane, Google Scholar and Google Patents. The search was limited to published literature written in the English language. Search terms were identical for each of...
Consequently, many wound care studies are of small scale and observational, constituting an immature body of knowledge with little transferability potential..
After applying a CTBP, as per manufacturer recommendation, to a variety of wound aetiologies and locations, a soft silicone wound contact layer was applied over the CTBP with overlap extending at...
Comparison of oxygen delivery therapies (not shown to scale). Hyperbaric oxygen treatment is given in a high-pressure chamber delivering 90 minutes of oxygen per day, five days per week. Topical...
Biofilms are communities of microbes that are either associated with biotic or abiotic surfaces (not necessarily solid) or are attached to themselves. They are encased in a matrix of extracellular...
A retrospective chart review of patients with DFUs who attended the FTA clinic at a large, inner-city, tertiary care, academic hospital between January 2008 and January 2013 was conducted. Patients...
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