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Polyhexamethylene biguanide and its antimicrobial role in wound healing: a narrative review

Subunit structure of polyhexamethylene biguanide (PHMB). Schematic structure of mono-protonated PHMB with chloride as counter-ion (a) and monomers: hexamethylenediamine (b) and sodium dicyanamide (c).

A 24-hour interval compression plan for managing chronic oedema: part 1—the science and theory behind the concept

The 24-hour interval compression plan creates a clinician and patient partnership using a compression regimen comprising a range of devices with dedicated self-selected intervals to remove, reapply or...

Health-related quality of life and assessment in patients with lower limb lymphoedema: a systematic review

We included published studies that assessed HRQoL in adults with LLL aged 18 and over. Only articles reported in the English language were included. Studies that were conducted using participants with...

Evaluation of a five-layer hydrocellular polyurethane foam dressing across wound care settings in southern Europe

The reduction in dressing change frequency observed here align with prior evaluations of the HPFD.2–3 The mechanism of T3 training delivery demonstrated in this evaluation has enabled these benefits...

The role of macronutrients and micronutrients in wound healing: a narrative review

When an acute wound initially takes place, an efflux of lymphatic fluid and blood occurs, resulting in the first phase of the wound healing process: haemostasis. This phase, usually triggered within...

Use of a bilayer biodegradable synthetic dermal matrix for the management of defects arising from necrotising fasciitis

Care can be divided into two overlapping phases. The first aim is the expedient surgical control of infection to achieve wound control and medical management of the effects of sepsis (e.g.,...

The influence of adequate debridement and placental-derived allografts on diabetic foot ulcers

Prospectively collected data from patients enrolled in two Institutional Review Board-approved RCTs (EFDFU003 and ECDFU001),14,22 and Medicare claims from 2015–2019 were retrospectively evaluated..

Treating hard-to-heal ulcers: biocellulose with nanosilver compared with silver sulfadiazine

To evaluate the efficacy of biocellulose with blue nanosilver, compared with silver sulfadiazine cream in the treatment of hard-to-heal diabetic ulcers..

Topical oxygen treatment relieves pain from hard-to-heal leg ulcers and improves healing: a case report

A 74-year-old male patient with insulin-treated type 1 diabetes for more than 50 years, and with a previous history of foot ulceration, was referred to the Karolinska University Hospital dermatology...

Healing outcomes and predictors among patients with venous leg ulcers treated with compression therapy

A search was conducted on the PubMed and CINAHL databases from 2009–2019, using MeSH key terms of ‘venous leg ulcers’, ‘compression therapy’, ‘delayed healing’, ‘non-healing’ and ‘wound healing’. The...

Chronic venous insufficiency: a comprehensive review of management

A comprehensive literature review of medical textbooks and journals was undertaken. Chapters and articles discussing the pathophysiology of CVI and its sequelae were included. A PubMed search of...

A dual pressure indicator, two-layer compression system for treatment of venous leg ulcers: a review

The two-layer bandage with pressure indicators (UrgoKTwo Compression Bandage with PresSure System, Urgo Medical, France) (2LB+I) comprises two dynamic layers: the short-stretch layer combines viscose...

Cost-effectiveness of dehydrated human amnion/chorion membrane allografts in lower extremity diabetic ulcer treatment

DHACM FPFU was associated with lower overall costs in the first year, despite higher treatment costs. This cost saving was due to lower amputation rates and lower healthcare resource utilisation (for...

The efficacy of sodium hypochlorite antiseptic: a double-blind, randomised controlled pilot study

This prospective, randomised, double-blind pilot study, conducted at a single outpatient wound care centre located in Western Pennsylvania, US, evaluated the efficacy of a topical antiseptic (Anasept)...

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