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Ulcer

Use of hypothermically stored amniotic membrane on diabetic foot ulcers: microbiological, immunological, clinical and therapeutic distinctions

Patient records from seven clinics in the Northeast, Southeast, Midwest, and Mid-Atlantic regions of the US were screened, and a total of 50 patients met inclusion criteria for the study..

Treating hard-to-heal ulcers: biocellulose with nanosilver compared with silver sulfadiazine

To evaluate the efficacy of biocellulose with blue nanosilver, compared with silver sulfadiazine cream in the treatment of hard-to-heal diabetic ulcers..

Topical oxygen treatment relieves pain from hard-to-heal leg ulcers and improves healing: a case report

A 74-year-old male patient with insulin-treated type 1 diabetes for more than 50 years, and with a previous history of foot ulceration, was referred to the Karolinska University Hospital dermatology...

Concurrent validity of biofilm detection by wound blotting on hard-to-heal wounds

This study showed concurrent validity with reference to native PAGE analysis for identifying and quantifying biofilm components through in vitro, in vivo and clinical investigations, as well as...

Healing outcomes and predictors among patients with venous leg ulcers treated with compression therapy

A search was conducted on the PubMed and CINAHL databases from 2009–2019, using MeSH key terms of ‘venous leg ulcers’, ‘compression therapy’, ‘delayed healing’, ‘non-healing’ and ‘wound healing’. The...

A dual pressure indicator, two-layer compression system for treatment of venous leg ulcers: a review

The two-layer bandage with pressure indicators (UrgoKTwo Compression Bandage with PresSure System, Urgo Medical, France) (2LB+I) comprises two dynamic layers: the short-stretch layer combines viscose...

The efficacy of sodium hypochlorite antiseptic: a double-blind, randomised controlled pilot study

This prospective, randomised, double-blind pilot study, conducted at a single outpatient wound care centre located in Western Pennsylvania, US, evaluated the efficacy of a topical antiseptic (Anasept)...

Clinical and cost efficacy of advanced wound care matrices in the treatment of venous leg ulcers: a systematic review

We sought to analyse products that have been identified in the literature as advanced matrices in the treatment of VLUs. These products were determined to be: advanced matrix (AM) (Talymed, Marine...

A guillotine amputation at the ankle level—how to quickly remove a septic foot: a case report

A 62-year-old female patient with poorly controlled diabetes and hypertension presented to a local medical centre's emergency department for evaluation of her right foot. One month before, while...

Topical oxygen therapy in the treatment of diabetic foot ulcers: a multicentre, open, randomised controlled clinical trial

This was a multicentre, open-label, randomised clinical trial conducted in 19 outpatient centres, geographically spread across the US. The primary objective of the study was to investigate the healing...

Disrupting the biofilm matrix improves wound healing outcomes

Existing technologies directed to the treatment of biofilms are intended to either penetrate the EPS that encapsulates the bacteria in a biofilm, or use dispersing agents, which typically target a...

Recommendations for the management of biofilm: a consensus document

There is more published evidence on the effectiveness of debridement in diabetic foot ulcers (DFUs) than for venous leg ulcers (VLUs) and pressure ulcers (PUs).8 After debridement, systemic...

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