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Skin substitutes

Cost-effectiveness of dehydrated human amnion/chorion membrane allografts in lower extremity diabetic ulcer treatment

DHACM FPFU was associated with lower overall costs in the first year, despite higher treatment costs. This cost saving was due to lower amputation rates and lower healthcare resource utilisation (for...

Observed impact of skin substitutes in lower extremity diabetic ulcers: lessons from the medicare database (2015–2018)

In the analysed dataset, 9,738,760 patients had a confirmed diabetes diagnosis, within which the metagroup of 909,813 had a confirmed diagnosis of LEDU, spanning 1,336,415 treatment episodes (Fig 1)....

The deteriorating DFU: prioritising risk factors to avoid amputation

The three risk factors for amputation illustrated as three intersecting rings of dominance (adapted from Armstrong and Mills)1.

A comparative analysis of skin substitutes used in the management of diabetic foot ulcers

DFUs that do not heal with standard care alone can be successfully treated with skin substitutes. However, these skin substitutes can be expensive, and once their use is initiated, treatment may still...

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