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Extracellular matrix

Cost-effectiveness of dehydrated human amnion/chorion membrane allografts in lower extremity diabetic ulcer treatment

DHACM FPFU was associated with lower overall costs in the first year, despite higher treatment costs. This cost saving was due to lower amputation rates and lower healthcare resource utilisation (for...

Fetal bovine acellular dermal matrix for the closure of diabetic foot ulcers: a prospective randomised controlled trial

This prospective multi-centre RCT demonstrated that FBADM plus SOC led to a significantly greater number of patients with DFUs achieving complete wound closure in 12 weeks compared with SOC alone. The...

Clinical and cost efficacy of advanced wound care matrices in the treatment of venous leg ulcers: a systematic review

We sought to analyse products that have been identified in the literature as advanced matrices in the treatment of VLUs. These products were determined to be: advanced matrix (AM) (Talymed, Marine...

Observed impact of skin substitutes in lower extremity diabetic ulcers: lessons from the medicare database (2015–2018)

In the analysed dataset, 9,738,760 patients had a confirmed diabetes diagnosis, within which the metagroup of 909,813 had a confirmed diagnosis of LEDU, spanning 1,336,415 treatment episodes (Fig 1)....

Surgical reconstruction of pilonidal sinus disease with concomitant extracellular matrix graft placement: a case series

A total of six patients were included in this case series (Table 1). The median age of patients was 25 years old. All patients had previously undergone I&D procedures and four patients had previously...

Extracellular matrix graft for reconstruction over exposed structures: a pilot case series

The retrospective case series was conducted in accordance with institutional guidelines conforming to the Declaration of Helsinki and informed written consent was obtained from patients. All patient...

Clinical application of a 3D-printed scaffold in chronic wound treatment: a case series

The objective of this case study is to evaluate the clinical application of a 3D-printed scaffold in the treatment of chronic wounds, including PUs and DFUs, including:.

Disrupting the biofilm matrix improves wound healing outcomes

Existing technologies directed to the treatment of biofilms are intended to either penetrate the EPS that encapsulates the bacteria in a biofilm, or use dispersing agents, which typically target a...

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