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Diabetic foot ulcer

Cold plasma treatment is safe for diabetic foot ulcers and decreases Staphylococcus aureus bacterial load

Between April 2016 and March 2018, we enrolled 20 patients. Two patients did not complete the two-week treatment period; one patient was admitted because of an infection at the ulcer site and one...

Healing hard-to-heal diabetic foot ulcers: the role of dehydrated amniotic allograft with cross-linked bovine-tendon collagen and glycosaminoglycan matrix

We evaluated a prospective case series of patients with complicated full-thickness ulcers, and comorbidities such as diabetes and peripheral vascular disease who were treated with DAMA (Integra...

Bacteriophage treatment of intransigent diabetic toe ulcers: a case series

More than 50% of diabetic foot ulcers (DFUs) become infected1 with ~18% resulting in minor amputation at best.2 The most common infective organism is meticillin-sensitive Staphylococcus aureus (MSSA),...

Comparison of two pixelated insoles using in-shoe pressure sensors to determine percent offloading: case studies

The under-use of TCCs is well-established in existing literature. Across the US, in 2010, TCC was used regularly in only 6% of wound care clinics.13 Despite higher healing rates achieved using TCC,...

Topical oxygen therapy in the treatment of diabetic foot ulcers: a multicentre, open, randomised controlled clinical trial

This was a multicentre, open-label, randomised clinical trial conducted in 19 outpatient centres, geographically spread across the US. The primary objective of the study was to investigate the healing...

Clinical application of a 3D-printed scaffold in chronic wound treatment: a case series

The objective of this case study is to evaluate the clinical application of a 3D-printed scaffold in the treatment of chronic wounds, including PUs and DFUs, including:.

Topical oxygen wound therapies for chronic wounds: a review

Different topical and systemic approaches of additional oxygen supply to a chronic wound are available. The topical approaches are discussed in this review in more detail.

The deteriorating DFU: prioritising risk factors to avoid amputation

The three risk factors for amputation illustrated as three intersecting rings of dominance (adapted from Armstrong and Mills)1.

A comparative analysis of skin substitutes used in the management of diabetic foot ulcers

DFUs that do not heal with standard care alone can be successfully treated with skin substitutes. However, these skin substitutes can be expensive, and once their use is initiated, treatment may still...

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