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Diabetes

Treating hard-to-heal ulcers: biocellulose with nanosilver compared with silver sulfadiazine

To evaluate the efficacy of biocellulose with blue nanosilver, compared with silver sulfadiazine cream in the treatment of hard-to-heal diabetic ulcers..

Topical oxygen treatment relieves pain from hard-to-heal leg ulcers and improves healing: a case report

A 74-year-old male patient with insulin-treated type 1 diabetes for more than 50 years, and with a previous history of foot ulceration, was referred to the Karolinska University Hospital dermatology...

A dual pressure indicator, two-layer compression system for treatment of venous leg ulcers: a review

The two-layer bandage with pressure indicators (UrgoKTwo Compression Bandage with PresSure System, Urgo Medical, France) (2LB+I) comprises two dynamic layers: the short-stretch layer combines viscose...

Cost-effectiveness of dehydrated human amnion/chorion membrane allografts in lower extremity diabetic ulcer treatment

DHACM FPFU was associated with lower overall costs in the first year, despite higher treatment costs. This cost saving was due to lower amputation rates and lower healthcare resource utilisation (for...

The efficacy of sodium hypochlorite antiseptic: a double-blind, randomised controlled pilot study

This prospective, randomised, double-blind pilot study, conducted at a single outpatient wound care centre located in Western Pennsylvania, US, evaluated the efficacy of a topical antiseptic (Anasept)...

Fetal bovine acellular dermal matrix for the closure of diabetic foot ulcers: a prospective randomised controlled trial

This prospective multi-centre RCT demonstrated that FBADM plus SOC led to a significantly greater number of patients with DFUs achieving complete wound closure in 12 weeks compared with SOC alone. The...

A guillotine amputation at the ankle level—how to quickly remove a septic foot: a case report

A 62-year-old female patient with poorly controlled diabetes and hypertension presented to a local medical centre's emergency department for evaluation of her right foot. One month before, while...

Observed impact of skin substitutes in lower extremity diabetic ulcers: lessons from the medicare database (2015–2018)

In the analysed dataset, 9,738,760 patients had a confirmed diabetes diagnosis, within which the metagroup of 909,813 had a confirmed diagnosis of LEDU, spanning 1,336,415 treatment episodes (Fig 1)....

Healing hard-to-heal diabetic foot ulcers: the role of dehydrated amniotic allograft with cross-linked bovine-tendon collagen and glycosaminoglycan matrix

We evaluated a prospective case series of patients with complicated full-thickness ulcers, and comorbidities such as diabetes and peripheral vascular disease who were treated with DAMA (Integra...

Extracellular matrix graft for reconstruction over exposed structures: a pilot case series

The retrospective case series was conducted in accordance with institutional guidelines conforming to the Declaration of Helsinki and informed written consent was obtained from patients. All patient...

Topical oxygen therapy in the treatment of diabetic foot ulcers: a multicentre, open, randomised controlled clinical trial

This was a multicentre, open-label, randomised clinical trial conducted in 19 outpatient centres, geographically spread across the US. The primary objective of the study was to investigate the healing...

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