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Chronic wound

Use of amniotic membrane in hard-to-heal wounds: a multicentre retrospective study

Cellular, acellular, and matrix-like products (CAMPs), in particular amniotic membranes (AM), represent a newer class of regenerative therapies that physically act as a skin barrier replacement, while...

Use of hypothermically stored amniotic membrane on diabetic foot ulcers: microbiological, immunological, clinical and therapeutic distinctions

Patient records from seven clinics in the Northeast, Southeast, Midwest, and Mid-Atlantic regions of the US were screened, and a total of 50 patients met inclusion criteria for the study..

Topical oxygen therapy stimulates healing in difficult, chronic wounds: a tertiary centre experience

Most wounds exhibit a degree of hypoxia, low oxygen levels lead to reduced rates of wound healing.

Concurrent validity of biofilm detection by wound blotting on hard-to-heal wounds

This study showed concurrent validity with reference to native PAGE analysis for identifying and quantifying biofilm components through in vitro, in vivo and clinical investigations, as well as...

The efficacy of sodium hypochlorite antiseptic: a double-blind, randomised controlled pilot study

This prospective, randomised, double-blind pilot study, conducted at a single outpatient wound care centre located in Western Pennsylvania, US, evaluated the efficacy of a topical antiseptic (Anasept)...

Topical oxygen therapy in the treatment of diabetic foot ulcers: a multicentre, open, randomised controlled clinical trial

This was a multicentre, open-label, randomised clinical trial conducted in 19 outpatient centres, geographically spread across the US. The primary objective of the study was to investigate the healing...

Use of wet-to-moist cleansing with different irrigation solutions to reduce bacterial bioburden in chronic wounds

All data analysed were collected as part of routine diagnosis and treatment, and patients were diagnosed and treated according to national guidelines and standards.8,9,10 All included patients gave...

Amniotic and umbilical cord particulate in the management of keloid and hypertrophic scars

Before initiating this study with human subjects, approval was obtained from Western Institutional Review Board (Washington, US). Written consent was obtained for the use of all details and...

Clinical application of a 3D-printed scaffold in chronic wound treatment: a case series

The objective of this case study is to evaluate the clinical application of a 3D-printed scaffold in the treatment of chronic wounds, including PUs and DFUs, including:.

Topical oxygen wound therapies for chronic wounds: a review

Different topical and systemic approaches of additional oxygen supply to a chronic wound are available. The topical approaches are discussed in this review in more detail.

Disrupting the biofilm matrix improves wound healing outcomes

Existing technologies directed to the treatment of biofilms are intended to either penetrate the EPS that encapsulates the bacteria in a biofilm, or use dispersing agents, which typically target a...

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