This website is intended for healthcare professionals
This website is intended for healthcare professionals
On 13 April 2020, the pulmonologist at Opelousas General Health System consulted the hyperbaric team for a 48-year-old African American woman complaining of severe shortness of breath with a...
To reflect best practice and transparency in reporting, this review was developed according to the recommendations described in the Preferred Reporting Items for Systematic Reviews and Meta-analysis...
Different topical and systemic approaches of additional oxygen supply to a chronic wound are available. The topical approaches are discussed in this review in more detail.
The aim of this article was to provide a focused commentary on the development of stem-cell therapies in burn care, rather than a systematic review. With this in mind, PubMed was searched for...
Contact allergies can occur frequently in patients with CLUs, even in those with a short duration of ulcerative disease, despite the use of new advanced dressings.8 The chronicity of venous...
Dumville et al.12 examined how debridement in leg ulcers of different aetiologies may reduce the bacterial burden in wounds. Leg ulcer patients were randomised (n=267) in three different groups...
Damage or stress causes cell necrosis. A necrotic cell loses membrane integrity and releases its intracellular contents including damage associated molecular patterns (DAMPs). These mediators may...
A microbial biofilm is an organised community of bacteria, enveloped within a self-produced matrix, that can attach, for example, to a wound surface (Fig 1).19 The formation of a differentiated,...
Inflammasomes are large, intracellular multi-protein complexes that play an important role in innate immunity. During consistent chronic wounding and repair processes, overactive and dysregulated...
The guidelines11 assign a strength of evidence to the studies included based on study design and quality. Level ‘A’ was assigned to recommendations supported by direct scientific evidence from...
The methodology applied to this research is that of a rapid review, which uses simplified components of the systematic review to produce synthesised evidence in a timely manner.16 According to O'Leary...
Early publications providing evidence for the presence of biofilm in chronic wounds have provided guidance for clinicians and researchers alike.10,11,39 These studies identified that biofilms were...