References

Ramundo JM. Wound Debridement, 5 edn. In: Bryant RA, Nix DP (eds). : Elsevier; 2016

Biofilms Made Easy. 2010. https://tinyurl.com/ybk6y2cr (accessed 11 September 2017)

Graninger M, Grassberger M, Galehr E Comments, opinions, and brief case reports: biosurgical debridement facilitates healing of chronic skin ulcers. Arch Intern Med. 2002; 162:(16)1906-1907 https://doi.org/10.1001/archinte.162.16.1906

Telgenhoff D, Shroot B. Cellular senescence mechanisms in chronic wound healing. Cell Death Differ. 2005; 12:(7)695-8 https://doi.org/10.1038/sj.cdd.4401632

Sussman C, Bates-Jensen B Skin and Soft Tissue Anatomy and Wound Healing Physiology in Sussman C, and Bates-Jensen B. Wound Care: A Collaborative Practice Manual, 4 edn. : Wolters Kluwer Health/Lippincott Williams & Wilkins; 2012

Hamm RL. Evaluation of the Patient with a Wound. In: Hamm RL (ed). : McGraw Hill; 2015

Friable. Farlex Partner Medical Dictionary. 2012. https://tinyurl.com/89vadb8 (accessed 31 August 2017)

Cutting KF, Harding KG. Criteria to identify wound infection. J Wound Care. 1994; 3:(4)198-120 https://doi.org/10.12968/jowc.1994.3.4.198

Lazaro JL, Izzo V, Meaume S, Davies AH Elevated levels of matrix metalloproteinases and chronic wound healing: an updated review of clinical evidence. J Wound Care. 2016; 25:(5)277-287 https://doi.org/10.12968/jowc.2016.25.5.277

Black J, Baharestani M, Black S An overview of the tissue types in pressure ulcers: a consensus panel recommendation. Ostomy Wound Manage. 2010; 56:(4)28-42

The role of proteases in wound diagnostics. An expert working group review.: Wounds International; 2011

Sinclair RD, Ryan TJ. Proteolytic enzymes in wound healing: the role of enzymatic debridement. Australas J Dermatol. 1994; 35:(1)35-41

Sibbald RG, Williamson D Preparing the wound bed - debridement, bacterial balance and moisture balance. Ostomy/Wound Management. 2000; 46:(11)14-35

Falanga V. Classifications for wound bed preparation and stimulation of chronic wounds. Wound Rep Regen. 2000; 8:347-352

Biofilms

Stay in the know with buzz words from the wound care circle: FOCUS: WOUND BED PREPARATION

02 October 2017
Resources
02 October 2017
Volume 1 · Issue 4

Autolysis: the natural physiologic process of disintegration of cells or tissues by endogenous enzymes; body's white blood cells and enzymes enter the wound site during the inflammatory phase of healing and liquefy the necrotic tissue; stimulated by a moist, vascular environment.1

Bioburden: degree of microbial contamination or microbial load; the number and effects of microorganisms contaminating a wound.

Biofilm: colonies of single bacterial or fungal species, or more commonly, polymicrobial organisms (bacterial, fungal, and possibly, viral) that group together and cover themselves with a slimy, glue-like protective coating (extracellular polymeric substance substance) to protect the colonies from outside invaders;2 biofilms can form on medical devices, in wounds, on sutures and many other surfaces.

Biosurgical debridement: the use of live sterile maggots to clean up and disinfect infected wounds; also known as maggot debridement therapy (MDT) or larval therapy.3

Cellular senescence: decreased or inability of a cell to proliferate/divide.4

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