Focus: atypical wounds

Antiphospholipid Syndrome: A hypercoagulable state that is associated with recurrent arterial and/or venous thrombosis, repeated fetal loss and/or elevated antiphospholipids

Calciphylaxis: A disorder, generally found in end stage renal disease (ERSD), but not limited to renal patients, with widespread calcification of small and medium sized vessels, which leads to occlusion, thrombosis, and tissue necrosis. Extreme cases can be life-threatening

Cryoglobulinemia: The presence of high levels of immunoglobulins in the blood which reversibly precipitates at cold temperatures. Aggregates of this protein can cause vessel occlusion in any organ, leading to tissue necrosis. Highly associated with hepatitis C infection

Eczema: Acute or chronic inflammatory conditions of the skin, typically erythematous, edematous, papular, vesicular, and crusting; it is followed often by lichenification and scaling, occasionally by change of the erythematous area to a dusky color, and infrequently by hyperpigmentation

Livedo reticularis: A net-like non-blanchable pattern of pigmentation on the skin, associated with vasculitis, microthrombic disorders, and cholesterol crystal embolisation