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Polyhexamethylene biguanide and its antimicrobial role in wound healing: a narrative review

Subunit structure of polyhexamethylene biguanide (PHMB). Schematic structure of mono-protonated PHMB with chloride as counter-ion (a) and monomers: hexamethylenediamine (b) and sodium dicyanamide (c).

A 24-hour interval compression plan for managing chronic oedema: part 1—the science and theory behind the concept

The 24-hour interval compression plan creates a clinician and patient partnership using a compression regimen comprising a range of devices with dedicated self-selected intervals to remove, reapply or...

Health-related quality of life and assessment in patients with lower limb lymphoedema: a systematic review

We included published studies that assessed HRQoL in adults with LLL aged 18 and over. Only articles reported in the English language were included. Studies that were conducted using participants with...

Evaluation of a five-layer hydrocellular polyurethane foam dressing across wound care settings in southern Europe

The reduction in dressing change frequency observed here align with prior evaluations of the HPFD.2–3 The mechanism of T3 training delivery demonstrated in this evaluation has enabled these benefits...

Genetic biases related to chronic venous ulceration

A literature review was conducted, via Medline, Pubmed and Sciencedirect (from January 1985 to September 2017) to identify research and other studies related to the genetic basis of chronic venous...

The role of macronutrients and micronutrients in wound healing: a narrative review

When an acute wound initially takes place, an efflux of lymphatic fluid and blood occurs, resulting in the first phase of the wound healing process: haemostasis. This phase, usually triggered within...

Diabetic foot ulcer management: the podiatrist's perspective

In 2010/11, 8.8% of all hospital admissions (with at least one overnight stay) for patients with diabetes involved a foot problem. There were 5917 non-traumatic lower extremity amputation admissions,...

The total contact cast: controversy in offloading the diabetic foot

Diabetic foot ulceration. The cumulative lifetime incidence may be as high as 15% .

Use of a bilayer biodegradable synthetic dermal matrix for the management of defects arising from necrotising fasciitis

Care can be divided into two overlapping phases. The first aim is the expedient surgical control of infection to achieve wound control and medical management of the effects of sepsis (e.g.,...

The influence of adequate debridement and placental-derived allografts on diabetic foot ulcers

Prospectively collected data from patients enrolled in two Institutional Review Board-approved RCTs (EFDFU003 and ECDFU001),14,22 and Medicare claims from 2015–2019 were retrospectively evaluated..